ILSC

santa barbara colloquium, ILSC 2015

Check back soon for upcoming International Light Scattering Colloquium dates!

Santa Barbara, CA

You don't know what you're missing if you haven't attended ILSC! Held on Santa Barbara's beautiful coast, you'll discover fabulous food, dolphins, great weather, and a wealth of information on light scattering in the service of science and industry.

Our guest speakers include prominent researchers from industry as well as academia, active in diverse areas including biotechnology, biomolecular chemistry, polymer chemistry, and nanotechnology. These seminars illuminate many ways in which analytical light scattering advances scientific research, offering opportunities for cross-pollination of novel ideas.

Please check back later for updates.

For more information, please contact programs@wyatt.com

 

2015 Short Courses

Introductory & advanced ½ day courses: MALS, DLS and more

Introductory and advanced light scattering courses covered introductions to techniques such as SEC-MALS, FFF-MALS, DLS, and CG-MALS, as well as offering refreshers on ASTRA or DYNAMICS software. The series of half-day courses were held at Wyatt Technology HQ, and were not only a great way to prepare for ILSC, but also a good excuse for traveling to Santa Barbara in November!

Course Title and Description
Time

Introduction to Light Scattering - Basics of multi-angle and dynamic light scattering: theory, instrumentation, and primary applications.

AM

ASTRA 6 - Refresher on ASTRA plus latest features and improvements and advanced training opportunities in SEC-MALS.

AM

DYNAMICS 7 - Refresher on DYNAMICS plus latest features and improvements and advanced training opportunities in DLS.

PM

FFF-MALS - Theory and use of Field-Flow Fractionation + Light Scattering (FFF-MALS) for separation and characterization of macromolecules and nanoparticles using the Wyatt Eclipse. Students should be familiar with Wyatt MALS instruments and ASTRA.

PM

CG-MALS - Theory and use of Composition-Gradient Light Scattering (CG-MALS) for characterization of biomolecular interactions using the Wyatt Calypso. Students should be familiar with Wyatt MALS instruments.

AM

MP-PALS - Theory and use of Phase Analysis Light Scattering with the Möbiuζ for characterization of macromolecular charge and nanoparticle zeta potential.

PM

2015 ILSC Photos

View Photos from the 2015 ILSC!

2015 ILSC

Wyatt's 24th ILSC "Light Scattering in the Nano World" was held on November 3-4, 2015 at the Four Seasons Biltmore Resort in Santa Barbara, CA.


Read a review by Dr. Robert L. Stevenson in American Laboratory.

Plenary Speakers

Vince Hackley, Ph.D. - National Institute of Standards and Technology
Project Team Leader, Nanoparticle Metrology for Health and the Environment

Quantitative Analysis of Functional Nanoparticles with an Introduction to NIST Reference Material Development for Nanotechnology Characterization

Vince Hackley

Frank von der Kammer, Ph.D. - University of Vienna
University Assistant, Vice Head of the Dept. of Environmental Sciences, Head of the Nanogeosciences Division and the Nanoparticle Analysis Laboratory

FFF-MALS-ICPMS Methods for the Analysis of Nanomaterials in Substances and Products

Frank von der Kammer

Paul Russo, Ph.D. - Georgia Tech
Professor of Materials Science and Engineering, Hightower Chair in Biopolymers

Light Scattering Measurements of Anisotropic Polymers and Colloids: Milking the Non-spherical Cow

Paul Russo

Philip Wyatt, Ph.D. - Wyatt Technology Corporation
CEO

Light Scattering and Nanoparticles… from its Long History to Proteins and Various Structures

Philip Wyatt

Light Scattering in Life Sciences, Chemistry and Biotechnology

Joseph Arndt, Ph.D. - Biogen
Senior Scientist, Chemistry & Molecular Therapeutics

Challenges of Maintaining Structure-Function Complexity of Protein Biologics Throughout the Manufacturing Process

Joseph Arndt

David Cistola, M.D., Ph.D. - University of North Texas Health Science Center
Vice President for Research & Innovation, Professor of Integrative Physiology & Anatomy, and Principal Investigator of the Nanoparticle Diagnostics Research Center

Profiling Nanoparticle and Microparticle Distributions in Human Blood using Dynamic Light Scattering and Other Biophysical Methods

David Cistola

Joseph Glajch, Ph.D. - Momenta Pharmaceuticals
Director of Analytical Development

SEC-MALS for the Characterization of Complex Drugs and Sugar-Protein Complexes of Immunological Importance

Joseph Glajch

Erica Ollmann-Saphire, Ph.D. - Scripps Research Institute
Professor of Immunology & Microbial Science; Co-Director, Center of Excellence, Global Virus Network

The Molecular Toolkit of Viral Hemorrhagic Fevers

Erica Ollmann-Saphire

Brian Shoichet, Ph.D. - UC San Francisco
Professor of Pharmaceutical Chemistry

Colloidal Aggregation in Drug Discovery & Pharmacology

Brian Shoichet

Short Courses were held Nov. 2, 2015

Introductory and advanced light scattering courses covered introductions to techniques such as SEC-MALS, FFF-MALS, DLS, and CG-MALS, as well as offering refreshers on ASTRA or DYNAMICS software. The series of half-day courses were held at Wyatt Technology HQ, and were not only a great way to prepare for ILSC, but also a good excuse for traveling to Santa Barbara in November! View course schedule.

 


Focus Meeting was held Nov. 5, 2015

A one day meeting focusing on method development for light scattering applications in the formulation of biotherapeutics was held after ILSC and addressed practical issues encountered in light scattering applications to biologic and small-molecule therapeutic formulation. Guest speakers from industry as well as Wyatt scientists discussed how they meet these challenges. View Focus Meeting schedule.

 

For more information, please contact programs@wyatt.com

2012 ILSC

2012 ILSC

Wyatt's 23rd ILSC was held on October 22-23, 2012 at the Four Seasons Biltmore Resort in Santa Barbara, CA.

2012 ILSC Photo Album

Plenary Speakers

  • Dr. Adrian Apetri, Crucell, Netherlands
    "Life in a Pharmaceutical Company Before and After Light Scattering"

  • Professor Annelise Barron, Stanford University
    "Studies of Yin/Yang Innate Immune Effectors May Be the Key to Understanding Human Neurodegenerative and Plaque Diseases"

  • Dr. Tapan Das, Pfizer Inc.
    "Predicting Aggregation Trend in Protein Therapeutics: Role of Biophysical Methods"

  • Dr. Stefan Fischer, F. Hoffmann-La Roche Ltd., Switzerland
    "Challenges in the Development of Protein Formulations"

  • Professor Stephen Harding, University of Nottingham, United Kingdom
    "MALS - A Success Story in Glycopolymer Research"

  • Professor Axel Mueller, University of Mainz, Germany
    "Self-Organized Multicompartment Nanostructures From New Triblock Terpolymers"

  • Professor Andre Nel, University of California, Los Angeles
    "Use of Nanomaterial Libraries and Their Characterization to Understand the Potential Environmental Impact of This Technology"

  • Professor Christopher Roberts, University of Delaware
    "Probing Protein Aggregation Mechanisms and Revisiting Protein-Protein Interactions from 'Low' to 'High' Concentrations"

  • Dr. Peter Schuck, National Institutes of Health
    "Protein Refractive Index Increments and the Structure and Function of Gamma Crystallin"

2011 ILSC

2011 ILSC

Wyatt's 22nd ILSC was held on October 31 - November 1, 2011 at the exclusive Four Seasons Biltmore Resort in Santa Barbara, CA.

2011 ILSC Photo Album

Plenary Speakers

  • Professor Ashutosh Chilkoti, Duke University
    "Self-Assembly of Recombinant Stimulus Responsive Polypeptide into Nanoparticles"

  • Dr. Ewa Folta-Stogniew, Yale University
    "Application of Light Scattering in a Core Facility Setting"

  • Professor Thomas Laue, University of New Hampshire
    "Protein Charge and Post-Reductionist Biochemistry"

  • Dr. Johannes Ottl, Novartis Pharma AG, Switzerland
    "Light Scattering In Pharmaceutical Low Molecular Weight Drug Discovery"

  • Dr. Robert Sitrin, Merck & Co. Inc.
    "Size Matters - Using Modern Technology to Characterize Vaccines"

  • Professor Andre Striegel, National Institute of Standards & Technology
    "7 Faces of Dr. Lao: The Many Roles of Light Scattering in Multi-Detector Polymer Separations"

  • Dr. Per-Olof Wahlund, Novo Nordisk A/S, Denmark
    "Light Scattering: A Useful Tool in the Biophysicist's Toolbox"

  • Dr. Germán Rivas, Centro de Investigaciones Biológicas, Spain
    "Quantitative Characterization of Essential Bacterial Macromolecular Complexes by Composition-Gradient Static Light Scattering Combined with Other Biophysical Techniques"

 

2010 ILSC

2009 ILSC

Wyatt's 21st ILSC was held on October 18 - 19, 2010 at the exclusive Four Seasons Biltmore Resort in Santa Barbara, CA.

Plenary Speakers

  • Dr. Christopher Johnson, Medical Research Council, United Kingdom
    "Fluctuation Correlation Spectroscopy: From Peptides to Molecular Machines"

  • Professor Krzysztof Matyjaszewski, Carnegie Mellon University
    "Nanostructured Functional Materials by Atom Transfer Radical Polymerization"

  • Dr. Michael McCarthy, MedImmune Inc.
    "Light Scattering in Biotech: It's Not Just About Aggregates (Although Sometimes It Is)"

  • Dr. Ed Moore, Baxter Healthcare
    "Heparin Molecular Weight Monitoring: A New USP Monograph Method for Unfractionated Heparin"

  • Dr. Linda Narhi, Amgen Inc.
    "Applications of Light Scattering Analysis During Protein Therapeutic Development"

  • Dr. David Narum, National Institutes of Health
    "Resolving Solution Structures of Malaria Proteins of Biological Interest and Vaccine Potential"

  • Dr. Robert Rambo, Lawrence Berkeley National Laboratories
    "Improving Small-Angle X-ray Scattering (SAXS) Based Modeling of Biological Macromolecules by Multi-Angle and Quasi-Elastic Light Scattering"

  • Professor Roger Tsien, University of California, San Diego
    "How Light Scattering Helps Us Characterize Molecular Spies"

  • Dr. Richard Vandlen, Genentech Inc.
    "Endowing Antibodies with New Functionalities"

 

Read about the 2010 ILSC in the American Laboratory Journal!

2009 ILSC

2009 ILSC

Wyatt's 20th ILSC was held on October 19 - 20, 2009 at the exclusive Four Seasons Biltmore Resort in Santa Barbara, CA.

Plenary Speakers

  • Dr. James Burns, Genzyme Corporation
    "Light Scattering and Product R&D at Genzyme"

  • Professor Angela Gronenborn, University of Pittsburgh
    "Shining Light on Protein-Protein Interactions: Synergy Between Scattering and NMR"

  • Professor Robert Grubbs, California Institute of Technology
    "Synthesis of Polymers of Precise Structures Using the Olefin Metathesis Reaction"

  • Professor Bruce Hamaker, Whistler Center for Carbohydrate Research, Purdue University
    "Application of Light Scattering Analysis to Changes in Food Carbohydrate Structures"

  • Professor Anton Middelberg, Centre for Biomolecular Engineering, University of Queensland, Australia
    "High-Resolution Quantitative Analysis of Compositionally Homogeneous Biomolecular Assemblies That Encode Quaternary Complexity"

  • Dr. Anil Patri, Nanotechnology Characterization Laboratory, National Cancer Institute at Frederick
    "Light Scattering Application in Cancer Nanotechnology"

  • Professor Andreas Plückthun, Biochemisches Institut, University of Zürich, Switzerland
    "Light Scattering as an Essential Tool in Protein Engineering"

  • Dr. Reb Russell, Protein Therapeutics Development, Bristol-Myers Squibb
    "The Use of Light Scattering for Protein Therapeutics' Characterization and Process Development"

 

Read about this event in the American Laboratory Journal!

2008 ILSC

2008 ILSC

Wyatt's 19th ILSC was held on October 20 - 21, 2008 at the elegant Bacara Resort & Spa in beautiful Santa Barbara, CA.

Read about our 2008 ILSC in American Biotechnology Laboratory: International Light Scattering Colloquium 2008: Molecules Happen

Plenary Speakers

  • Dr. Alan Herman, Windrose Analytica Inc.
    "Characterization, Comparability, and Process Optimization of Biopharmaceutical Proteins by SEC-MALS"

  • Dr. Jeffery Kelly, Scripps Research Institute
    "Proteostasis and Disease"

  • Professor Andre Palmer, Ohio State University
    "Light Scattering Analysis of Hemoglobin-Based Oxygen Carriers for Use in Transfusion Medicine"

  • Dr. John Philo, Alliance Protein Laboratories
    "Shedding Some Light On (and From) Protein Aggregates"

  • Dr. Hans-Joachim Schönfeld, F. Hoffmann-La Roche Ltd., Switzerland
    "Analysis of Absolute Protein Quaternary Structure by Using SEC or AF4 with On-line Light Scattering and Concentration Monitoring"

  • Dr. Blake Simmons, Sandia National Laboratories
    "Tracking Bioinspired Silicification with Static and Dynamic Light Scattering"

  • Dr. Mark Witmer, Bristol-Myers Squibb
    "Varied Applications of Light Scattering Methods in Drug Discovery Research"

2007 ILSC

2007 ILSC

Wyatt's 18th ILSC was held on October 15 - 16, 2007 at the Four Seasons Biltmore Resort in Santa Barbara, CA.

Plenary Speakers

  • Dr. Byron Caughey, NIH/NIAID Rocky Mountain Laboratories
    "The Most Infectious Prion Protein Particles"

  • Professor Howard Dintzis, Johns Hopkins School of Medicine
    "Some Protein Interactions as Studied By Photon Scattering Over the Decades"

  • Dr. Marshall Fishman, U.S. Department of Agriculture
    "Application of SEC, MALS, VIS, and Microscopy to the Structural Characterization of Plant Polysaccharides"

  • Dr. Wolfgang Fraunhofer, Abbott Bioresearch Center
    "Applications of Field Flow Fractionation, Static and Dynamic Light Scattering in the Development of Biopharmaceuticals"

  • Professor Andrew Lyon, Georgia Institute of Technology
    "Hydrogels in Physics and Biology"

  • Dr. Allen Minton, National Institutes of Health
    "Quantitative Characterization of Protein-Protein Interactions in Highly Concentrated Solution Via Measurement of Static Light Scattering and Other Colligative Properties"

  • Dr. Vincent Turula, Wyeth Vaccines
    "Application of SEC-MALS from Vaccine Development to Commercial Manufacturing"

  • Dr. Michael Washabaugh, Merck & Co. Inc.
    "Characterization & Comparability of Gardasil®, a Recombinant HPV Vaccine"

2006 ILSC

2006 ILSC

Wyatt's 17th ILSC was held on October 16 - 17, 2006 at the Four Seasons Biltmore Resort in Santa Barbara, CA.

Plenary Speakers

  • Dr. Bradford Powell, U.S. Army Medical Research Institute of Infectious Diseases
    "Light Scattering Analysis of the Yersinia pestis  Virulence Factors"

  • Professor Judit Puskas, University of Akron
    "Analysis of Novel Branched Biomaterials Using Multidetector SEC (MALS, VIS, QELS)"

  • Professor Terry Rosenberry, Mayo Clinic
    "Size Analysis of Beta-Amyloid Peptide Aggregates That Appear to Cause Alzheimer's Disease"

  • Professor Paul Russo, Louisiana State University
    "Goring Sacred Cows: Challenging Convention in Polymer and Particle Analysis"

  • Dr. Steven Shire, Genentech Inc.
    "Assessment of Self - Association of Protein Therapeutics at High Concentration and Its Impact on Viscosity"

  • Professor William Balch, Scripps Research Institute
    "COPII Nanocages: Particle Self-Assembly in Human Health and Disease"

  • Dr. Stephen Raso, Wyeth Biopharma
    "Biophysical Analysis of Therapeutic Protein Complexes, Conjugates, and Conformations"

2005 ILSC

2005 ILSC

Wyatt's 16th ILSC was held October 24 - 25, 2005 at the Four Seasons Biltmore Resort in Santa Barbara, CA.

Plenary Speakers

  • Dr. George Heavner, Centocor Inc.
    "A Case Study in Protein/Surfactant Interactions: Erythropoietin in a Polysorbate 80 Formulation"

  • Dr. Barbara Bolgiano, National Institute for Biological Standards & Control, United Kingdom
    "Molecular Sizing of Bacterial Vaccines"

  • Dr. Angela Gronenborn, National Institutes of Health
    "Anything Goes - Protein Structure Polymorphism"

  • Professor Jean Frechet, University of California, Berkeley
    "Functional Macromolecules: Shape, Size, and Function"

  • Professor Tudor Arvinte, University of Geneva, Switzerland
    "Application of Field Flow Fractionation, Light Scattering, Spectroscopic and Microscopy Techniques in the Characterization of Therapeutic Proteins"

  • Professor Lin Randall, University of Missouri-Columbia
    "Asymmetric Binding Between SecA and SecB Two Symmetric Proteins: Implications for Function in Export"

  • Dr. Brent Larsen, Berlex Biosciences
    "Characterization of Virus-like Particle Assembly for Plasmid Delivery Using the Wyatt Asymmetric Field Flow Fractionation Instrument"

  • Professor Annelise Barron, Northwestern University
    "A Key Role for MALS in Characterizing High-Molar Mass Polymers and Nanogels for DNA Sequencing by Microchannel Electrophoresis"

2004 ILSC

Wyatt's 15th ILSC was held October 11 - 12, 2004 at the Four Seasons Biltmore Resort in Santa Barbara, CA.

2004 Plenary Speakers

Plenary Speakers

  • Professor Marguerite Rinaudo, Centre de Recherches sur les Macromolécules Végétales, France
    "Analysis of Some Polysaccharides Using SEC Associated with a Light Scattering Detector"

  • Professor John van Zanten, North Carolina State University
    "Stickin' Together: MALLS and Aggregation/Complexation Phenomena"

  • Dr. Ed Moore, Baxter Healthcare
    "Protein Biopharmaceuticals - When Big Becomes Too Big"

  • Dr. Allen Minton, National Institutes of Health
    "New MALS Techniques for Quantitative Characterization of Macromolecular Interactions in Solution"

  • Dr. Edward Eisenstein, Center for Advanced Research in Biotechnology
    "The Joy of Discovering Size Exclusion Chromatography and Light Scattering for Protein Characterization in Structural and Functional Genomics"

  • Professor Rudy Faust, University of Massachusetts at Lowell
    "Synthesis and Micellar Properties of Amphiphilic Block Copolymer Architectures"

  • Professor Cassandra Fraser, University of Virginia
    "Polymeric Metal Complexes: Synthesis, Biomaterials Applications, and Responsive Nanoscale Assemblies"

  • Dr. Girija Krishnamurthy, Wyeth Research
    "Characterizing the interactions of small molecule inhibitors with target protein using MALS"

2003 ILSC

2003 ILSC

Wyatt's 14th ILSC was held September 22 - 23, 2003 in Santa Barbara, CA.

Plenary Speakers

  • Dr. Steven Berkowitz, Biogen Corporation
    "Measuring the Aggregation of Biopharmaceuticals When SEC is Not Feasible, Using Light Scattering Coupled to Other Separation Techniques"

  • Professor Robert Grubbs, California Institute of Technology
    "Linear, Block and Cyclic Polymers by Olefin Metathesis"

  • Professor S.E. Harding, University of Nottingham, United Kingdom
    "The 2nd Thermodynamic Virial Coefficient and the Size, Shape, Hydration, Self-association and Crystallisation of Proteins"

  • Professor Joseph Horwitz, University of California, Los Angeles
    "The Structure and Function of the Eye Lens Small Heat-Shock Protein: Alpha-Crystallin"

  • Professor Jimmy Mays, University of Tennessee
    "Solution Properties of Model Branched Polymers"

  • Professor Charles McCormick, University of Southern Mississippi
    "Precise Structural Control of Water-Soluble (Co)Polymers Utilizing RAFT Techniques"

  • Dr. Paul Ramage, Novartis, Switzerland
    "The Use of Field Flow Fractionation-coupled Light Scattering to Monitor Protein Refolding"

  • Professor Emeritus Walter Stockmayer, Dartmouth College
    "Landmarks in the History of Light Scattering in Multicomponent Systems"

2002 ILSC

Wyatt's 13th ILSC was held October 21 - 22, 2002 at the Four Seasons Biltmore Resort in Santa Barbara, CA.

Four Seasons Biltmore Hotel

Plenary Speakers

  • Professor Walther Burchard, University of Freiburg, Germany
    "The Power of Static and Dynamic Light Scattering in Combination with Viscometry"

  • Professor R. John Collier, Harvard University
    "Assembly of Anthrax Toxin Complexes"

  • Professor Adi Eisenberg, McGill University, Canada
    "Self-assembly for Asymmetric Amphiphilic Diblock Copolymers into Aggregates of Various Morphologies"

  • Dr. John Hennessey, Merck & Co. Inc.
    "Molecular Size Specifications for a Multivalent Polysaccharide Vaccine"

  • Professor Tim Lodge, University of Minnesota
    "Anomalous Micellization in Block Copolymers: A Case Study of Inadequate Characterization"

  • Professor Jacques Penelle, University of Massachusetts at Amherst
    "Measuring the Absolute Molecular Weights of Synthetic Polymers: Current Status and Remaining Challenges"

  • Dr. Ewa Folta-Stogniew, Yale University School of Medicine
    "Analysis of Protein Complexes by Size Exclusion Chromatography Coupled with Light Scattering"

  • Dr. Bengt Wittgren, AstraZeneca, Sweden
    "MALS - A Necessary Tool for Advanced Characterisation of Polymers and Sub-Micron Particles"

Focus Meetings

These one day focus meetings, held in conjunction with the ILSC, address practical issues encountered in light scattering applications and focus on a specific application or technique. Guest speakers from industry as well as Wyatt scientists join to discuss how they meet these challenges.The Eclipse Field-Flow Fractionation (FFF) Focus Meetings are dedicated to the exchange of experiences between users of the Eclipse FFF system where the application focus was proteins, biopolymers and liposome/virus particles. The Dynamic Light Scattering (DLS) Focus Meetings provide Wyatt DLS users to relate both positive experiences as well as the difficulties encountered and resolved. The Formulations meetings discuss method development for light scattering applications in the formulation of biotherapeutics.


See what happened in previous years!

2015 Formulations Focus Meeting

Method development for light scattering applications in the formulation of biotherapeutics

This one day focus meeting, held on November 5, 2015 directly after the ILSC, addressed practical issues encountered in light scattering applications to biologic and small-molecule therapeutic formulation. Guest speakers from industry as well as Wyatt scientists discussed how they meet these challenges.

Guest Speakers

Dennis Leung, Ph.D. - Merck & Co.
Principal Scientist, Discovery Pharmaceutical Sciences Group, Merck Research Laboratories

High-Throughput Tools for Optimizing Drug Nanosuspension Formulations

Dennis Leung 

Michael Marlow, Ph.D. - Regeneron Pharmaceuticals
Senior Staff Scientist, Biochemical and Biophysical Characterization

Challenges in Biotherapeutic Coformulation, Opportunities for Light Scattering

Michael Marlow 

Martijn Schenning, Ph.D. - Janssen
Senior Scientist, Vaccine Process and Analytical Development

Vaccine Product Characterization by AF4-MALS: Particle Size Distribution and Aggregation

Martijn Schenning 

2012 DLS Focus Meeting

The Dynamic Light Scattering (DLS) Focus Meeting was held on October 24, 2012 and was dedicated to the exchange of experiences between users of Wyatt DLS systems. Both positive experiences as well as difficulties encountered and how these issues were resolved were discussed. The meeting consisted of plenary talks structured along different topics, each followed by a round-table discussion. Wyatt R&D and Support staff were on hand to join in on the discussions and to hear how we can improve the software and instrumentation.

Speakers

  • Dr. John Champagne, Wyatt Technology
    "Protein Charge Determination: The Theory and Practice of Relating Protein Charge to Solution Behavior"

  • Ms. Stephanie Cope, Arizona State University
    "Using All Your Angles: Multi-Angle DLS of Polymers with Slow Internal Motion"

  • Dr. Youngchang Kim, Argonne National Laboratory
    "Application of DLS in Structural Genomics"

  • Professor Andrew MacKay, University of Southern California
    "Therapeutic Protein Polymer Nanoparticles"

  • Dr. Vladimir Razinkov, Amgen Inc.
    "High-Throughput DLS-based Methods in Biopharmaceutical Drug Development"

  • Dr. Jingtao Zhang, Merck & Co. Inc.
    "Light Scattering of siRNA Drug Delivery System"

2011 Eclipse FFF Focus Meeting

The 2011 Eclipse Field-Flow Fractionation (FFF) - MALS Focus Meeting was held on November 2nd at the Four Seasons Biltmore Resort in Santa Barbara, CA.

The meeting was dedicated to the exchange of experiences between users of the Eclipse FFF system, and focused on protein, biopolymers and liposome/virus particle applications. The meeting consisted of round-table discussions, structured along different topics. For each session there was a talk given by an expert in the corresponding topic as an introduction to the general discussion.

Speakers

  • Dr. Wei Gao, Dow Chemical Company
    "Probe the TiO2-Polymer Composite Formation in a New Class of Latex Paint by AFFFF-MALS"

  • Dr. Christoph Johann, Wyatt Technology Europe GmbH
    "New Developments in Flow-FFF Instrumentation: Hollow-Fiber Flow-FFF and Frit-Inlet Flow-FFF"

  • Mr. Joey Pollastrini, Amgen Inc.
    "FFF Applied in Biotech: Case Scenarios and Commentary"

  • Mr. Michael Smith, Georgia Institute of Technology
    "AF4-MALS for Temporal Analysis of Degradable Nanogels"

  • Dr. Frédéric Violleau, Ecole d'Ingénieurs de Purpan
    "Analysis of Food Protein with AsF1FFF-MALS"

FFF Meeting
Read about our 2010 FFF-MALS Focus Meeting in the American Laboratory Journal!

2010 Eclipse FFF Focus Meeting

The 2010 Eclipse Field-Flow Fractionation (FFF) - MALS Focus Meeting was held on October 20th at the Four Seasons Biltmore Resort in Santa Barbara, CA.

The meeting was dedicated to the exchange of experiences between users of the Eclipse FFF system, and focused on protein, biopolymers and liposome/virus particle applications. The meeting consisted of round-table discussions, structured along different topics. For each session there was a talk given by an expert in the corresponding topic as an introduction to the general discussion.

Speakers

  • Dr. Janice Davis, Althea Technologies
    "AF4 for Protein Formulation Evaluation and Analysis of Large Proteins"

  • Mr. Cliff Entrican, Pfizer Wyeth Biopharma
    "Biophysical Support of Vaccine Process Changes: Field-Flow Fractionation and Multi-Angle Light Scattering as a Tool to Characterize Large, Polydisperse Protein-Polysaccharide Conjugates"

  • Dr. Stepan Podzimek, SYNPO a.s
    "Comparison of SEC and Asymmetric Flow FFF in Characterization of Molecular Structure of Synthetic and Natural Polymers"

  • Dr. Dierk Roessner, Wyatt Technology Europe GmbH
    "Optimization of AF4 Method Development using Simulation Tools: New Software Developments for coupling of ASTRA and Eclipse"

FFF Meeting
Read about our 2010 FFF-MALS Focus Meeting in the American Laboratory Journal!

2009 Eclipse FFF Focus Meeting

The 2009 Eclipse FFF-MALS Focus Meeting was dedicated to the exchange of experiences between users of the Eclipse FFF system, and focused on protein, biopolymers and liposome/virus particle applications. The meeting consisted of round-table discussions, structured along different topics. For each session there was a talk given by an expert in the corresponding topic as an introduction to the general discussion.

Speakers

  • Dr. Shawn Cao, Amgen Inc.
    "Characterizing Protein Aggregates with Field-Flow Fractionation"

  • Dr. Jan-Martijn Hamelink, GlaxoSmithKline
    "The Role Of AFFF in Antigen Characterization"

  • Professor Jason Unrine, University of Kentucky
    "Use of AF4-MALS-ICPMS for In Situ  Characterization of Metals and Engineered Nanomaterials in Environmental and Biological Samples"

2008 Eclipse FFF Focus Meeting

The 2008 Eclipse FFF-MALS Focus Meeting was dedicated to the exchange of experiences between users of the Eclipse FFF system, and focused on protein, biopolymers and liposome/virus particle applications. The meeting consisted of round-table discussions, structured along different topics. For each session there was a talk given by an expert in the corresponding topic as an introduction to the general discussion.

Speakers

  • Dr. Bradford Powell, U.S. Army Medical Research Institute of Infectious Diseases
    "Antibody-Antigen Characterization by FFF/MALS"

  • Dr. Hans-Joachim Schönfeld, F. Hoffmann-La Roche AG
    "Asymmetrical-Flow Field-Flow-Fractionation (AF4) and Size Exclusion Chromatography (SEC) with On-Line Light Scattering and Concentration Monitoring are Orthogonal Methods to Analyze Reconstituted High Density Lipoprotein (rHDL) Particles"

  • Dr. Stepan Podzimek, SYNPO a.s
    "Characterization of Synthetic and Natural Polymers by A4F-MALS"

  • Dr. Wyatt Vreeland, National Institutes of Standards and Technology
    "Microfluidic Directed Assembly of Engineering Vesicle Nanoparticles: Interesting and Unexpected Effects Revealed by Light Scattering"

  • Dr. Dierk Roessner, Wyatt Technology Europe GmbH
    "Extending the Limits of AFFFF: Optimizing Resolution from ng to mg Sample Load"

2007 Eclipse FFF Focus Meeting

The 2007 Eclipse FFF-MALS Focus Meeting was dedicated to the exchange of experiences between users of the Eclipse FFF system, and focused on protein, biopolymers and liposome/virus particle applications. The meeting consisted of round-table discussions, structured along different topics. For each session there was a talk given by an expert in the corresponding topic as an introduction to the general discussion.

  • Session 1: AF4 as a Tool for the Characterization of Proteins and in Protein Formulation
    Professor Gerhard Winter, LMU University Munich

  • Session 2: Characterization of Liposomes and Colloid Particles with AF4
    Professor Martin Brandl, University Tromsoe

  • Session 3: Method Development and Optimization of AF4 Experiments
    Dr. Dierk Roessner, Wyatt Technology Europe

  • Session 4: Hardware and Software Developments in AF4
    Dr. Christoph Johann, Wyatt Technology Europe